The combination of lincomycin and spectinomycin acts additive and in some cases synergistic. Spectinomycin acts bacteriostatic or bactericidal, depending on the dose, against mainly Gram-negative bacteria like Campylobacter, E. coli, Salmonella spp. and Mycoplasma. Lincomycin acts bacteriostatic against mainly Gram-positive bacteria like Staphylococcus and Streptococcus spp. and Mycoplasma. Cross-resistance of lincomycin with macrolides can occur.
Gastrointestinal and respiratory infections caused by lincomycin and spectinomycin sensitive micro-organisms, like Campylobacter, E. coli, Mycoplasma, Salmonella, Staphylococcus, Streptococcus and Treponema spp. in calves, cats, dogs, goats, poultry, sheep, swine and turkeys.
Hypersensitivity reactions.
Shortly after injection a slight pain, itching or diarrhoea can occur.
For intramuscular or subcutaneous (poultry, turkeys) administration:
Calves: 1 ml per 10 kg body weight for 4 days.
Goats and sheep: 1 ml per 10 kg body weight for 3 days.
Swine: 1 ml per 10 kg body weight for 3 – 7 days.
Cats and dogs: 1 ml per 5 kg body weight for 3 – 5 days, maximally 21 days.
Poultry and turkeys: 0.5 ml per 2.5 kg body weight for 3 days.
For meat:
Calves, goats, sheep and swine: 14 days.
Poultry and turkeys: 7 days.
For milk: 3 days.
Store below 25ºC, in a cool and dry place, and protect from light.