• xbxc1
Enrofloxacin is a broad-spectrum bactericidal drug for animals in the flurofenolone class. Escherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Actinobacillus pleuropneumoniae, Erysipelas, Proteus, Serratia marcescens, Corynebacterium pyogenes, Portella septicarum It has a good effect on bacteria, Staphylococcus aureus, mycoplasma, chlamydia, etc., 
but has a weak effect on Pseudomonas aeruginosa and Streptococcus and a weak effect on anaerobic bacteria. It has obvious antibacterial post-effect on sensitive bacteria.
This product is rapidly and completely absorbed by intramuscular injection. The bioavailability of this product is 91.9% in pigs and 82% in dairy cows. It is widely distributed in animals and can easily enter tissues and body fluids. Except for cerebrospinal fluid, the drug concentration in almost tissues is higher than that in blood.
Pulp. Liver metabolism mainly involves the removal of the ethyl group of the 7-crosin ring to generate ciprofloxacin, followed by oxidation and glucuronic acid conjugation, mainly excreted through the kidneys (by renal tubular secretion and glomerular filtration), 15% to 50% Excreted unchanged in urine. Eliminate half
The lifespan varies greatly in different species of animals and different routes of administration. The elimination half-life after intramuscular injection.
medicine interactions:
(1) This product has a synergistic effect when combined with amino sugars or broad-spectrum penicillin.
(2) Heavy metal ions such as Ca2+, Mg2+, Fe; and Al Children may interact with this product and affect absorption.
(3) When used in combination with theophylline and caffeine, the plasma protein binding rate can be reduced, the concentration of theophylline and caffeine in the blood will increase abnormally, and even symptoms of theophylline poisoning may occur.
(4) This product has the effect of inhibiting liver drug enzymes and can reduce the clearance rate of drugs that are mainly metabolized in the liver.
Function and use:
Flufenolone antibiotics. Used for bacterial diseases and mycoplasma infections in livestock and poultry.
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Post time: Apr-26-2024