Diclazuril is an anticoccidial of the benzene acetonitrile group and has an anticoccidial activity against Eimeria species. Depending on the coccidia species, diclazuril has a coccidiocidal effect on the asexual or sexual stages of the development cycle of the parasite. Treatment with diclazuril causes interruption of the coccidial cycle and of excretion of oocysts for approximately 2 to 3 weeks after administration. This allows the lambs to bridge the period of decrease of maternal immunity (observed at approximately 4 weeks of age) and calves to reduce the infection pressure of their environment.
For the treatment and prevention of coccidial infections in lambs caused in particular by the more pathogenic Eimeria species, Eimeria crandallis and Eimeria ovinoidalis.
To aid in the control of coccidiosis in calves caused by Eimeria bovis and Eimeria zuernii.
To ensure the correct dosage, bodyweight should be determined as accurately as possible.
1 mg diclazuril per kg bodyweightas a single administration.
Diclazuril solution was given to lambs as a single dose up to 60 times the therapeutic dose. No adverse clinical effects were reported.
No adverse effects were noted either at 5 times the therapeutic dose administered four consecutive times with a 7-day interval.
In calves, the product was tolerated when administered up to five times the recommended dose rate.
Meat and offal:
Lambs: zero days.
Calves: zero days.
Store below 25ºC, in a cool and dry place, and protect from light.