Oxytetracycline belongs to the group of tetracyclines and acts bacteriostatic against many Gram-positive and Gram-negative bacteria like Bordetella, Bacillus, Corynebacterium, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. and Mycoplasma, Rickettsia and Chlamydia spp. The mode of action of oxytetracycline is based on inhibition of bacterial protein synthesis. Oxytetracycline is mainly excreted in urine and to a lesser degree in bile and in lactating animals in milk.
Gastrointestinal and respiratory infections caused by oxytetracycline sensitive bacteria like Bordetella, Bacillus, Corynebacterium, Campylobacter, E. coli, Haemophilus, Pasteurella, Salmonella, Staphylococcus and Streptococcus spp. and Mycoplasma, Rickettsia and Chlamydia spp. in calves, goats, poultry, sheep and swine.
Hypersensitivity to tetracyclines.
Administration to animals with an impaired renal and/or liver function.
Concurrent administration of penicillines, cephalosporines, quinolones and cycloserine.
Administration to animals with an active microbial digestion.
Discoloration of teeth in young animals.
Hypersensitivity reactions.
For oral administration:
Calves, goats and sheep : Twice daily 1 gram per 20 – 40 kg body weight for 3 – 5 days.
Poultry and swine : 1 kg per 2000 litre drinking water for 3 – 5 days.
Note: for pre-ruminant calves, lambs and kids only.
- For meat:
Calves, goats, sheep and swine : 8 days.
Poultry : 6 days.